self-antigen
Americannoun
Etymology
Origin of self-antigen
First recorded in 1970–75
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
“Basically, you need three ingredients: self-antigen, an inflammatory environment and autoimmune predisposition,” he says.
From Scientific American • Sep. 14, 2021
In peripheral tolerance, functional, mature B cells leave the bone marrow but have yet to be exposed to self-antigen.
From Textbooks • Jun. 19, 2013
One explanation for the breakdown of tolerance is that, after certain bacterial infections, an immune response to a component of the bacterium cross-reacts with a self-antigen.
From Textbooks • Jun. 19, 2013
As T and B cells mature, there are mechanisms in place that prevent them from recognizing self-antigen, preventing a damaging immune response against the body.
From Textbooks • Jun. 19, 2013
When a B cell binds to a self-antigen but receives no signals from a nearby Th2 cell to produce antibody, the cell is signaled to undergo apoptosis and is destroyed.
From Textbooks • Jun. 19, 2013
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
