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sertraline

American  
[sur-truh-leen] / ˈsɜr trəˌlin /

noun

Pharmacology.
  1. a drug, C 17 H 17 NCl 2 HCl, of the SSRI class, used in the treatment of depression.


Etymology

Origin of sertraline

First recorded in 1980–85; shortening of ser(otonin) (te)tra-(naphtha)l(ene) (am)ine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

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That earlier research found that sertraline eased anxiety before it had a measurable impact on depression.

From Science Daily Nov. 8, 2025

Many people have been helped by antidepressants, the most common of which are so-called selective serotonin reuptake inhibitors, or SSRIs, including sertraline, also known as Zoloft, and escitalopram—brand name Lexapro.

From The Wall Street Journal Oct. 19, 2025

He later returned to the surgery, saying they were not making him feel better and his doctor moved him from sertraline to citalopram, a similar drug.

From BBC Jan. 10, 2025

The antidepressants sertraline and paroxetine, both greenlit by FDA in 2000, generally have a small effect and work in less than two-thirds of patients, Rothbaum notes.

From Science Magazine Jun. 5, 2024

Moreover, at least one antidepressant, sertraline, promoted the transfer of genes between bacterial cells, a process that can speed up the spread of resistance through a population.

From Scientific American Jan. 26, 2023

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