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St. Louis

American  
[seynt loo-is] / ˌseɪnt ˈlu ɪs /

noun

  1. a port in E Missouri, on the Mississippi.

  2. a river in NE Minnesota, flowing generally S to Lake Superior at Duluth. 160 miles (257 km) long.


St. Louis Cultural  
  1. The largest city in Missouri.


Discover More

Known as the “Gateway to the West” because of its importance as a staging area for wagon trains in the nineteenth century. The Gateway Arch, made of steel and several hundred feet high, stands in St. Louis in commemoration of this fact.

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

“I think this is a test for the new chair,” said former St. Louis Fed President James Bullard, in an interview with MarketWatch.

From MarketWatch • May 30, 2026

“I think this is a test for the new chair,” said former St. Louis Fed President James Bullard, in an interview with MarketWatch.

From MarketWatch • May 30, 2026

There’s the investment manager of the endowment at Washington University in St. Louis who plunked down $50 million into SpaceX External link nearly a decade ago, which is now worth in excess of $1 billion.

From Barron's • May 29, 2026

The comments come at a delicate time for LAFC, which has let potential MLS wins slip away despite showing competitive moments recently against St. Louis City SC and Nashville SC.

From Los Angeles Times • May 24, 2026

St. Louis air smelled of tar and doughnuts, old boards washed up out of the muddy river, red bricks, and licorice.

From "Habibi" by Naomi Shihab Nye

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