St. Louis

American  

[seynt loo-is] / ˌseɪnt ˈlu ɪs /

noun

1. a port in E Missouri, on the Mississippi.

2. a river in NE Minnesota, flowing generally S to Lake Superior at Duluth. 160 miles (257 km) long.

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St. Louis Cultural  

1. The largest city in Missouri.

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Known as the “Gateway to the West” because of its importance as a staging area for wagon trains in the nineteenth century. The Gateway Arch, made of steel and several hundred feet high, stands in St. Louis in commemoration of this fact.

Example Sentences

On Aug. 24, 1974, he stole five bases in a game against the St. Louis Cardinals, becoming the first NL player to do so since 1904.

From Los Angeles Times • Apr. 8, 2026

Chair Jerome Powell, Kansas City Fed President Jeffrey Schmid, and St. Louis Fed President Alberto Musalem have all warned in the past few weeks that longer term expectations could drift higher if inflation stays elevated.

From Barron's • Apr. 8, 2026

St. Louis Fed President Alberto Musalem will speak at 9:05 a.m., and later Fed Gov. Michael Barr will deliver comments.

From MarketWatch • Apr. 1, 2026

Another earned his Ph.D. from Washington University in St. Louis, and helped develop the Covid-19 vaccine at Pfizer.

From The Wall Street Journal • Mar. 25, 2026

Both Ma Charles and Miss Trotter nodded, especially to the St. Louis part, like she had said, “Paris, France.”

From "Gone Crazy in Alabama" by Rita Williams-Garcia