mutations

Cultural  

1. Changes in chromosomes or genes that cause offspring to have characteristics different from those of their parents. Mutations can be caused by the effects of chemicals, radiation, or even ordinary heat on DNA. Mutations produce some of the differences between members of a species on which natural selection acts.

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Example Sentences

Mice that carry genetic mutations associated with a higher risk of Alzheimer's disease begin developing amyloid beta plaques that fill the brain by about six months of age.

From Science Daily

For example, mutations in genes that produce CoA transporters have been linked to encephalopmyopathy, a condition that may involve developmental delays, epilepsy, and reduced muscle tone.

From Science Daily

"It could help explain why tumors of different origins, even when carrying the same mutations, often respond very differently to chemotherapy, radiotherapy, or targeted inhibitors," says Dr. Sdelci.

From Science Daily

Scientific theory suggests that increasing population size allows more opportunities for genetic reshuffling and the appearance of new mutations.

From Science Daily

The team then applied the same strategy to cells taken from patients with Rett syndrome who carry MECP2 mutations that reduce protein levels and activity.

From Science Daily