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synthetase

American  
[sin-thuh-teys, -teyz] / ˈsɪn θəˌteɪs, -ˌteɪz /

noun

Biochemistry.
  1. ligase.


Etymology

Origin of synthetase

First recorded in 1947; synthet(ic) + -ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

First, the researchers purified the glutamine synthetase -- the enzyme responsible for the energy-dependent uptake of nitrogen -- from both organisms and checked its activity.

From Science Daily • Jan. 22, 2024

The enzyme amino acyl tRNA synthetase would lose control over the amino acid.

From Textbooks • Jun. 9, 2022

The chemical similarities between DAP, serine and cysteine amino-acid residues made it difficult for the authors to engineer an amino acyl-tRNA synthetase that selectively loads only the ncAA.

From Nature • Dec. 11, 2018

Athletes with less training have less of the enzyme that restores glycogen — glycogen synthetase.

From New York Times • Jan. 16, 2012

Cancer cells that happen to have the synthetase enzyme are not affected by asparaginase, so the chemical would be wasted in attempts to treat patients with cancerous cells of this type.

From Time Magazine Archive