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termination codons

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Premature termination codons activate the NMD pathway, which leads to rapid degradation of PTC+ transcripts, and have been associated with transcriptional regulation during disease and stress response in human and Arabidopsis, respectively.

From Nature Dec. 5, 2012

Abundant alternative splicing, premature termination codons and novel transcriptionally active regions suggest that post-transcriptional processing forms an important regulatory layer.

From Nature Dec. 5, 2012

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