theobromine

American  

[thee-uh-broh-meen, -min] / ˌθi əˈbroʊ min, -mɪn /

noun

Pharmacology.

1. a white, crystalline, water-insoluble, poisonous powder, C 7 H 8 N 4 O 2 , an isomer of theophylline and lower homologue of caffeine, occurring in tea and obtained from the cacao bean: used chiefly as a diuretic, myocardial stimulant, and vasodilator.

---

theobromine British  

/ -mɪn, ˌθiːəʊˈbrəʊmiːn /

noun

1. a white crystalline slightly water-soluble alkaloid that occurs in many plants, such as tea and cacao: formerly used to treat asthma. Formula: C 7 H 8 N 4 O 2 See also xanthine

---

theobromine Scientific  

/ thē′ō-brō′mēn′ /

1. A bitter, colorless alkaloid that occurs in the cacao bean, cola nuts, and tea. It is found in chocolate products and used in medicine as a diuretic, vasodilator, and myocardial stimulant. Theobromine is a xanthine and similar in structure to caffeine and theophylline. Chemical formula: C ₇ H ₈ N ₄ O ₂ .

---

Etymology

Origin of theobromine

1835–45; < New Latin Theobrom ( a ) genus of trees typified by cacao (< Greek theo- theo- + brôma food) + -ine ²

Compare meaning

How does theobromine compare to similar and commonly confused words? Explore the most common comparisons:

• theobromine vs. caffeine

Example Sentences

Researchers at King's College London have identified theobromine, a plant compound found in cocoa, as a possible contributor to this effect.

From Science Daily • Dec. 12, 2025

The lack of theobromine also means that unlike chocolate, carob is not toxic to dogs and cats.

From Seattle Times • Apr. 8, 2024

It's well documented that the ingestion of caffeine and theobromine is highly toxic for domestic animals.

From Salon • Mar. 28, 2024

Cocoa bean mulch, which contains caffeine and theobromine, can cause vomiting and diarrhea, among other issues.

From Washington Post • May 4, 2022

This cacao has a bold bean and a fine flavour, and is rich in theobromine; it is much valued on the market, and its strength and character render it indispensable to the manufacturer.

From The Food of the Gods A Popular Account of Cocoa by Head, Brandon