fibrinogen

American  

[fahy-brin-uh-juhn] / faɪˈbrɪn ə dʒən /

noun

Biochemistry.

1. a globulin occurring in blood and yielding fibrin in blood coagulation.

---

fibrinogen British  

/ ˌfaɪbrɪnəʊˈdʒɛnɪk, ˌfaɪbrɪˈnɒdʒənəs, fɪˈbrɪnədʒən /

noun

1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

---

fibrinogen Scientific  

/ fī-brĭn′ə-jən /

1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

---

Other Word Forms

• fibrinogenic
  adjective

Etymology

Origin of fibrinogen

First recorded in 1870–75; fibrino- + -gen

Compare meaning

How does fibrinogen compare to similar and commonly confused words? Explore the most common comparisons:

• fibrin vs. fibrinogen

Example Sentences

See Examples For:

fibrinogen

A humanized antibody that blocks the inflammatory region of fibrinogen is currently in phase-1 trials after animal studies showed protection against neuronal loss.

From Science Daily ● Jan. 8, 2026

When Aβ attaches to fibrinogen, it produces unusual clots that resist breakdown.

From Science Daily ● Oct. 22, 2025

"It takes a larger amount of Aβ or fibrinogen alone to cause serious damage in the Alzheimer's brain," says Erin Norris, research associate professor in the laboratory of Sidney Strickland at Rockefeller.

From Science Daily ● Oct. 22, 2025

In a separate analysis, the team examined health records from nearly 50,000 people in the U.S.—including some who had taken blood tests for fibrinogen or D-dimer before the pandemic started.

From Scientific American ● Sep. 1, 2023

It is not yet certain what is the nature of the final reaction between fibrinogen and thrombin.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various