transgenic

[trans-jen-ik, tranz‑]

adjective

1. of, relating to, or containing a gene or genes transferred from another species.

   transgenic mice.

transgenic

/ trænzˈdʒɛnɪk /

adjective

1. (of an animal or plant) containing genetic material artificially transferred from another species

transgenic

1. Relating to an organism whose genome has been altered by the transfer of a gene or genes from another species or breed. Transgenic organisms are used in research to help determine the function of the inserted gene, while in industry they are used to produce a desired substance.

Word History and Origins

Origin of transgenic¹

First recorded in 1980–85

Example Sentences

The new therapeutic technique has been validated in vivo in transgenic mice expressing the human PCSK9 gene.

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"The results show that both HpE9 and HpE12 are highly effective in HepG2 cells. HpE12 decreases PCSK9 RNA levels by 74% and protein levels by 87%. In the case of transgenic mice, a single injection of HpE12 reduces plasma PCSK9 levels by 50% and cholesterol levels by 47% on the third day," says Professor Verònica Noé.

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The main metabolite, aminomethylphosphonic acid, was detected in the brains of both normal and transgenic mice with Alzheimer's pathology.

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Transgenic mice are genetically modified to carry genes that cause them to develop Alzheimer's-like symptoms as they age.

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The study, "Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models," appears in the November 26 issue of Cell Reports.

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