• synonyms


noun Biochemistry.
  1. a proteolytic enzyme of the pancreatic juice, capable of converting proteins into peptone.
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Origin of trypsin

1875–80; irregular < Greek trîps(is) friction (trī́b(ein) to rub + -sis -sis) + -in2; so called because first obtained by rubbing the pancreas
Related formstryp·tic [trip-tik] /ˈtrɪp tɪk/, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

Examples from the Web for trypsin

Historical Examples of trypsin

  • The second enzym to be considered in the pancreatic juice is trypsin.

    Encyclopedia of Diet

    Eugene Christian

  • It is digested by trypsin and slowly destroyed by the fat solvent anæsthetics, such as chloroform.

  • Luciferase is destroyed only by pepsin (probably), trypsin, erepsin, and something in spleen and liver extract.

  • Thus, in experiments168 on blood-fibrin it was found that, while a solution of trypsin containing 0.5 per cent.

    On Digestive Proteolysis

    R. H. Chittenden

  • The pepsin of the gastric juice and the trypsin of the pancreas split the native proteins only to peptones.

    The Fundamentals of Bacteriology

    Charles Bradfield Morrey

British Dictionary definitions for trypsin


  1. an enzyme occurring in pancreatic juice: it catalyses the hydrolysis of proteins to peptides and is secreted from the pancreas in the form of trypsinogenSee also chymotrypsin
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Derived Formstryptic (ˈtrɪptɪk), adjective

Word Origin for trypsin

C19 tryp-, from Greek tripsis a rubbing, from tribein to rub + -in; referring to the fact that it was originally produced by rubbing the pancreas with glycerine
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for trypsin


chief digestive enzyme of pancreatic juice, 1876, apparently from Greek tripsis "rubbing" + chemical suffix -in (2). Said to be so called because it first was obtained by rubbing the pancreas with glycerin.

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Online Etymology Dictionary, © 2010 Douglas Harper

trypsin in Medicine


  1. An enzyme of pancreatic juice that hydrolyzes proteins into smaller polypeptide units.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

trypsin in Science


  1. An enzyme that aids digestion by breaking down proteins. It is produced by the pancreas and secreted into the small intestine, where it catalyzes the cleavage of peptide bonds connecting arginine or lysine to other amino acids.
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The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.