trypsinogen

American  

[trip-sin-uh-juhn, -jen] / trɪpˈsɪn ə dʒən, -ˌdʒɛn /

noun

Biochemistry.

1. a precursor of trypsin that is secreted by the pancreas and is activated to trypsin in the small intestine.

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trypsinogen British  

/ trɪpˈsɪnədʒən /

noun

1. the inactive precursor of trypsin that is converted to trypsin by the enzyme enterokinase

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Etymology

Origin of trypsinogen

First recorded in 1885–90; trypsin + -o- + -gen

Example Sentences

Once released into the small intestine, an enzyme found in the wall of the small intestine, called enterokinase, binds to trypsinogen and converts it into its active form, trypsin.

From Textbooks • Jun. 19, 2013

The intestinal brush border enzyme enteropeptidase stimulates the activation of trypsin from trypsinogen of the pancreas, which in turn changes the pancreatic enzymes procarboxypeptidase and chymotrypsinogen into their active forms, carboxypeptidase and chymotrypsin.

From Textbooks • Jun. 19, 2013

In the pancreas, vesicles store trypsin and chymotrypsin as trypsinogen and chymotrypsinogen.

From Textbooks • Jun. 19, 2013

When trypsinogen extracted from pancreas is added to trypsin, the trypsin begins to multiply.

From Time Magazine Archive

This phenomenon has a close analog in the behavior of a well-known protein: trypsinogen, inactive precursor of the enzyme trypsin.

From Time Magazine Archive