wakefulness
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a word derived from
wakeful.
wakefuladjectiveunable to sleep; not sleeping; indisposed to sleep.
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
The FDA approved the first medication to treat narcolepsy by targeting a brain chemical that regulates wakefulness.
From The Wall Street Journal ● Aug. 7, 2026
"This suggests that sleep and growth hormone form a tightly balanced system: Too little sleep reduces growth hormone release, and too much growth hormone can in turn push the brain toward wakefulness," Silverman said.
From Science Daily ● Mar. 30, 2026
After showing signs of wakefulness, he was transferred to the Sid Watkins Rehabilitation Centre in Liverpool on 23 December that year.
From BBC ● Mar. 1, 2026
After poor sleep, the brain tries to compensate during wakefulness, triggering pulses of fluid that coincide with sharp reductions in attention, according to a recent study published in Nature Neuroscience.
From The Wall Street Journal ● Feb. 13, 2026
In that half-world between sleep and wakefulness, I can almost hear the ringing of a hammer on steel and the dry hiss of the arc welder at the little machine shop by the tipple.
From "October Sky" by Homer Hickam
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