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autoimmune

American  
[aw-toh-i-myoon] / ˌɔ toʊ ɪˈmjun /

adjective

Immunology.
  1. of or relating to the immune response of an organism against any of its own tissues, cells, or cell components.


autoimmune British  
/ ˌɔːtəʊɪˈmjuːn /

adjective

  1. (of a disease) caused by the action of antibodies produced against substances normally present in the body

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of autoimmune

First recorded in 1950–55; auto- 1 + immune

Explanation

When a condition or illness is described as autoimmune, it means the body's immune system is attacking the body's own cells or tissues. Lupus is one example of an autoimmune disease. Your immune system sends out antibodies to attack bacteria and viruses that shouldn't be in your body. When this system mistakenly attacks substances that are meant to be in your body, it can cause all kinds of problems — this is an autoimmune disorder. Autoimmune is a medical term that's been around since the 1950s, from auto-, "self," and immune, "exempt from a disease."

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Vocabulary lists containing autoimmune

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Rheumatoid arthritis is an autoimmune disease in which the immune system mistakenly attacks tissue around the joints, causing pain, swelling, stiffness, and potentially long-term damage.

From Science Daily Sep. 13, 2026

As I was recuperating, he was diagnosed with an autoimmune condition, which meant he had to tap out indefinitely.

From Los Angeles Times Sep. 11, 2026

Rheumatoid arthritis is an autoimmune condition in which the immune system attacks the synovium, the tissue that lines the joints.

From Science Daily Sep. 5, 2026

She was admitted to hospital four days before her death with kidney and autoimmune issues.

From BBC Sep. 4, 2026

“I don’t know. It just happens to some people. That’s the way autoimmune diseases are.”

From "How to Disappear Completely" by Ali Standish

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