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a suffix found in French loanwords of Latin origin, usually diminutives, and later in adaptations of words borrowed directly from Latin or in Neo-Latin coinages:
areole; centriole; vacuole.
Origin of -ole1
< French < Latin -olus, -ola, -olum, variant of -ulus -ule with stems ending in a vowel


a suffix used in names of chemical compounds, especially five-membered, unsaturated rings (carbazole; indole; thiazole) and, less systematically, aromatic ethers (anisole; safrole).
Also, -ol2 .
< French < Latin oleum oil Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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British Dictionary definitions for -ole


combining form
denoting an organic unsaturated compound containing a 5-membered ring: thiazole
denoting an aromatic organic ether: anisole
Word Origin
from Latin oleum oil, from Greek elaion, from elaia olive


indicating something small: arteriole
Word Origin
from Latin -olus, diminutive suffix
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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-ole in Medicine

-ole or -ol

  1. A usually heterocyclic chemical compound containing a five-membered ring: pyrrole.

  2. A chemical compound, especially an ether, that does not contain hydroxyl: indole.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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