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[an-ti-his-tuh-meen, -min] /ˌæn tɪˈhɪs təˌmin, -mɪn/
noun, Physiology, Pharmacology.
any of certain compounds or medicines that neutralize or inhibit the effect of histamine in the body, used chiefly in the treatment of allergic disorders and colds.
Origin of antihistamine
First recorded in 1930-35; anti- + histamine Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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British Dictionary definitions for antihistamines


/ˌæntɪˈhɪstəˌmiːn; -mɪn/
any drug that neutralizes the effects of histamine, used esp in the treatment of allergies
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for antihistamines



1933, from anti- + histamine.

Online Etymology Dictionary, © 2010 Douglas Harper
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antihistamines in Medicine

antihistamine an·ti·his·ta·mine (ān'tē-hĭs'tə-mēn', -mĭn)
Any of several drugs used to counteract the physiological effects of histamine.

an'ti·his'ta·mine' adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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antihistamines in Science
Any of various drugs that relieve cold or allergy symptoms by blocking the action of histamine.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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antihistamines in Culture
antihistamines [(an-tee-his-tuh-meenz, an-tee-his-tuh-muhnz)]

Drugs that counteract the effects of a substance in the body called histamine. The body releases histamine, which causes many of the symptoms associated with allergies (sneezing, watery eyes, runny nose), in response to external agents such as pollen.

The New Dictionary of Cultural Literacy, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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