Old English dust, from Proto-Germanic *dunstaz (cf. Old High German tunst "storm, breath," German Dunst "mist, vapor," Danish dyst "milldust," Dutch duist), from PIE *dheu- (1) "dust, smoke, vapor" (cf. Sanskrit dhu- "shake," Latin fumus "smoke"). Meaning "that to which living matter decays" was in Old English, hence, figuratively, "mortal life."
Literally, to fall face down in the dirt; to suffer a defeat: “Once again, the champion wins, and another contender bites the dust.”
Narcotics in powder form (1960s+ Narcotics)
Storms of sand and dust sometimes overtake Eastern travellers. They are very dreadful, many perishing under them. Jehovah threatens to bring on the land of Israel, as a punishment for forsaking him, a rain of "powder and dust" (Deut. 28:24). To cast dust on the head was a sign of mourning (Josh. 7:6); and to sit in dust, of extreme affliction (Isa. 47:1). "Dust" is used to denote the grave (Job 7:21). "To shake off the dust from one's feet" against another is to renounce all future intercourse with him (Matt. 10:14; Acts 13:51). To "lick the dust" is a sign of abject submission (Ps. 72:9); and to throw dust at one is a sign of abhorrence (2 Sam. 16:13; comp. Acts 22:23).