- a yellowish-white layer consisting of leukocytes that, upon centrifugation of blood, covers the red blood cells.
Origin of buffy coat
First recorded in 1790–1800
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- The upper, lighter portion of the blood clot occurring when coagulation is delayed or when blood has been centrifuged.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.