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[kuh-kek-tin] /kəˈkɛk tɪn/
Biochemistry, Immunology. a protein that is released by activated macrophages as an immune system defense and, when the defense is overwhelmed, is a cause of cachexia or toxic shock: in humans, identical with tumor necrosis factor.
Origin of cachectin
< Greek kachekt(ikós) unwell (see cachexia, -tic) + -in2 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2017.
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cachectin in Medicine

cachectin ca·chec·tin (kə-kěk'tĭn)
A polypeptide hormone produced by macrophages that releases fat and reduces the concentration of enzymes needed to produce and store fat.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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