- Biochemistry, Immunology. a protein that is released by activated macrophages as an immune system defense and, when the defense is overwhelmed, is a cause of cachexia or toxic shock: in humans, identical with tumor necrosis factor.
Origin of cachectin
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- A polypeptide hormone produced by macrophages that releases fat and reduces the concentration of enzymes needed to produce and store fat.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.