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[en-doh-noo-klee-eys, -eyz, -nyoo-] /ˌɛn doʊˈnu kliˌeɪs, -ˌeɪz, -ˈnyu-/
noun, Biochemistry.
any of a group of enzymes that degrade DNA or RNA molecules by breaking linkages within the polynucleotide chains.
Origin of endonuclease
First recorded in 1960-65; endo- + nuclease Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2017.
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British Dictionary definitions for endonuclease


an enzyme that is responsible for scission of a nucleic acid chain, the action of which is not confined to the terminal nucleotide Compare exonuclease
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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endonuclease in Medicine

endonuclease en·do·nu·cle·ase (ěn'dō-nōō'klē-ās', -āz', -nyōō'-)
Any of a group of enzymes that catalyze the hydrolysis of phosphodiester bonds between nucleic acids in a DNA molecule or an RNA sequence.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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