estradiol

[es-truh-dahy-awl, -ol]

noun

1. Biochemistry.,  an estrogenic hormone, C 18 H 24 O 2 , produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.

2. Pharmacology.,  a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.

estradiol

/ ˌɛstrəˈdaɪɒl, ˌiːstrə- /

noun

1. the US spelling of oestradiol

Word History and Origins

Origin of estradiol¹

1930–35; estra- (combining form representing estrin ) + di- ¹ + -ol ¹

Example Sentences

It typically consists of taking estradiol—delivered through pills, patches, gels and sprays—often given in combination with oral progesterone to reduce the risk of uterine cancer.

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The hormone estradiol could also be used to alleviate menopause symptoms like hot flashes and night sweats, and progesterone could be used to protect the uterine lining and improve sleep quality.

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Taken together, the results extend previous findings indicating that women with early bilateral oophorectomy are at high risk for Alzheimer's disease due to a link between APOE4 and estradiol loss in this cohort.

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When the couple’s older child was 19, living at home as a college student, Mrs. James got a call from the pharmacy informing her that her child’s prescription for estradiol, or estrogen, was ready.

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The researchers engineered the yeast to degrade proteins essential for life unless estradiol, a type of oestrogen, was present.

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