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[im-yuh-noh-di-fish-uh n-see, ih-myoo-] /ˌɪm yə noʊ dɪˈfɪʃ ən si, ɪˌmyu-/
noun, plural immunodeficiencies.
impairment of the immune response, predisposing to infection and certain malignancies.
Origin of immunodeficiency
First recorded in 1970-75; immuno- + deficiency
Related forms
immunodeficient, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2018.
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British Dictionary definitions for immunodeficiency


a deficiency in or breakdown of a person's immune system
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for immunodeficiency

1969, from comb. form of immune + deficiency.

Online Etymology Dictionary, © 2010 Douglas Harper
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immunodeficiency in Medicine

immunodeficiency im·mu·no·de·fi·cien·cy (ĭm'yə-nō-dĭ-fĭsh'ən-sē, ĭ-myōō'-)
A disorder or deficiency of the normal immune response. Also called immune deficiency.

im'mu·no·de·fi'cient adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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immunodeficiency in Science
  (ĭm'yə-nō-dĭ-fĭsh'ən-sē, ĭ-my'-)   
The inability to produce a normal immune response, caused by an acquired or inherited disease.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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