- a member of an American Indian people, formerly part of the Creek Confederacy and surviving chiefly as one of the two branches of the Muskogean family represented among the Florida Seminoles.
- the Muskogean language of the Mikasuki.
Origin of Mikasuki
< a native town name
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018