"negative reply," early 13c., from Old English na (adv.) "no, never, not at all," from ne "not, no" + a "ever." First element from Proto-Germanic *ne (cf. Old Norse, Old Frisian, Old High German ne, Gothic ni "not"), from PIE root *ne "no, not" (see un-). Second element from PIE *aiw- "vital force, life, long life, eternity" (see aye (2)).
As an adjective meaning "not any" (c.1200) it is reduced from Old English nan (see none), the final -n omitted first before consonants and then altogether. As a noun from c.1300. Phrase no can do "it is not possible" is attested from 1827, a locution of English-speaking Chinese noted 19c. in China, Australia and West Coast of U.S.
We repeated our advice again and again, but got no answer but a loud horse-laugh, and their national maxim of No can do: Europe fashion no do in China. ["Reminiscences of a Voyage to and from China," in "Paxton's Horticultural Register," London, 1836]Construction no X, no Y attested from 1530s (in no peny no pardon). No problem as an interjection of assurance first attested 1963. No way as an expression meaning "it can't be done" is attested by 1968.
The symbol for the element nobelium.
The symbol for nobelium.
A synthetic, radioactive metallic element in the actinide series that is produced by bombarding curium with carbon ions. Its longest-lived isotope is No 255 with a half-life of 3.1 minutes. Atomic number 102. See Periodic Table.