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prostaglandin

American  
[pros-tuh-glan-din] / ˌprɒs təˈglæn dɪn /

noun

  1. Biochemistry. any of a class of unsaturated fatty acids that are involved in the contraction of smooth muscle, the control of inflammation and body temperature, and many other physiological functions.

  2. Pharmacology. any commercial preparation of this substance.


prostaglandin British  
/ ˌprɒstəˈɡlændɪn /

noun

  1. any of a group of potent hormone-like compounds composed of essential fatty acids and found in all mammalian tissues, esp human semen. Prostaglandins stimulate the muscles of the uterus and affect the blood vessels; they are used to induce abortion or birth

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

prostaglandin Scientific  
/ prŏs′tə-glăndĭn /
  1. Any of a group of substances that are derived from fatty acids and have a wide range of effects in the body. Prostaglandins influence the contraction of the muscles lining many internal organs and can lower or raise blood pressure.


Etymology

Origin of prostaglandin

First recorded in 1935–40; prosta(te) + gland 1 + -in 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The compound significantly reduced contractions triggered by several signaling molecules, including acetylcholine, histamine, prostaglandin F2α, and serotonin.

From Science Daily Jul. 30, 2026

Earlier research from Blau's lab showed that prostaglandin E2 is essential for muscle stem cell function.

From Science Daily Jan. 20, 2026

By blocking 15-PGDH or increasing prostaglandin E2 levels, researchers previously supported the repair of damaged muscle, nerve, bone, colon, liver, and blood cells in young mice.

From Science Daily Jan. 20, 2026

When they blocked the release of prostaglandin E2 in cancer tissue, the T cells showed better expansion and were thus able to fight human cancer cells more effectively.

From Science Daily Apr. 24, 2024

This appears to be related to increased prostaglandin synthesis, which is important for inducing contractions, and the onset of labor, Engeland explained.

From Science Daily Mar. 6, 2024

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