- See under Rh factor.
Origin of Rh negative
First recorded in 1955–60
- any of a type of specific antigen present on the surface of red blood cells, persons having inherited such antigens being designated Rh+ (Rh positive) and persons lacking them, a much smaller group, being designated Rh− (Rh negative): blood of Rh− persons is incompatible with Rh+ blood because of antibody reaction, and an Rh− woman who bears an Rh+ baby will have formed antibodies to the fetal blood that, unless removed from her bloodstream by apheresis in a subsequent pregnancy, will be carried across the placenta and destroy red blood cells of the next Rh+ fetus, resulting in erythroblastosis in the newborn.
Origin of Rh factor
First recorded in 1940–45; so called because first found in the blood of rhesus monkeys
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- blood that does not contain the Rh factor
- a person having such blood
C20: named after the rhesus monkey, in which it was first discovered
Word Origin and History for rh-negative
1942, from the first letters of rhesus; so called because the blood group, and its effects, were discovered in the blood of rhesus monkeys (1941).
Online Etymology Dictionary, © 2010 Douglas Harper
- Lacking an Rh factor.
- Any of several substances on the surface of red blood cells that induce a strong antigenic response in individuals lacking the substance.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
- Any of several antigens present on the surface of red blood cells in most humans. People with Rh factors are classified as having a blood type that is Rh positive, while people who lack the antigen are said to be Rh negative and can produce powerful antibodies that destroy red blood cells if given a blood transfusion from an Rh-positive donor. A woman who is Rh negative and is pregnant with an Rh-positive fetus can produce antibodies that are life threatening to the fetus. See Note at blood type.
The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Any of several substances found on the surface of red blood cells in persons.
An Rh-negative woman who gives birth to an Rh-positive baby may develop antibodies to the Rh factor during her first pregnancy. These antibodies may cause a disorder in Rh-positive babies conceived afterward that could result in the death of the infant if the condition is not recognized and treated.
The New Dictionary of Cultural Literacy, Third Edition Copyright © 2005 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.