Dictionary.com
Thesaurus.com
Synonyms

senescent

American  
[si-nes-uhnt] / sɪˈnɛs ənt /

adjective

  1. growing old; aging.

  2. Cell Biology. (of a cell) no longer capable of dividing but still alive and metabolically active.


senescent British  
/ sɪˈnɛsənt /

adjective

  1. growing old

  2. characteristic of old age

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Derived Forms

Etymology

Origin of senescent

First recorded in 1650–60; from Latin senēscent- (stem of senēscēns ) present participle of senēscere “to grow old,” equivalent to sen- “old” + -ēscent- -escent

Explanation

Something senescent is growing old or is elderly. Senescent things are deteriorating. Senescent and senile have something in common — the Latin root senex which means "old.” A baby or even a teenager would not be described as senescent because they're youthful and full of life. A nursing home is full of people who could be described as senescent; they’re old. "The Who" was going to sing “hope I die before I get senescent,” but it just didn’t have the same ring to it.

Keep Reading on Vocabulary.com

Vocabulary lists containing senescent

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Because of this complexity, anti-aging researchers are increasingly moving away from strategies that attempt to eliminate all senescent cells.

From Science Daily • May 22, 2026

Early senolytic drugs such as dasatinib, quercetin, and fisetin were developed to destroy senescent cells by disrupting the survival pathways that keep them alive.

From Science Daily • May 22, 2026

Some researchers are now investigating CAR-T cell immunotherapies that can recognize markers found on senescent cells and selectively remove them.

From Science Daily • May 22, 2026

Rather than viewing all senescent cells as dangerous, researchers increasingly believe the future of anti-aging medicine may depend on distinguishing harmful cells from beneficial ones.

From Science Daily • May 22, 2026

In one thin arm, threaded with veins in a kind of senescent bas-relief, was a basket.

From "The Great Santini" by Pat Conroy

Vocabulary.com logo
by dictionary.com

Look it up. Learn it forever.

Remember "senescent" for good with VocabTrainer. Expand your vocabulary effortlessly with personalized learning tools that adapt to your goals.

Take me to Vocabulary.com