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sis

[sis]
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noun Informal.
  1. sister.

Origin of sis

1825–35, Americanism; shortened form; compare Dutch zus for zuster sister

-sis

  1. a suffix appearing in loanwords from Greek, where it was used to form from verbs abstract nouns of action, process, state, condition, etc.: thesis; aphesis.

Origin of -sis

From Greek
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

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British Dictionary definitions for sis

sis1

noun
  1. informal short for sister

sis2

sies

interjection
  1. Southern African informal an exclamation of disgust

Word Origin

Afrikaans, possibly from Khoi

SIS

abbreviation for
  1. Also called: MI6 (in Britain) Secret Intelligence Service
  2. (in New Zealand) Security Intelligence Service
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for sis

n.

1650s, abbreviated form of sister; in American English, applied generally to girls and young women (1859). It also was the familiar short form of Cecilie, Cicely, a common name for girls in the Middle English period.

-sis

suffix in Greek-derived nouns denoting action, process, state, condition, from Greek -sis, which is identical in meaning with Latin -entia, English -ing (1).

Online Etymology Dictionary, © 2010 Douglas Harper