take leave of

1. Also, take one's leave of . Depart from, say good-bye to. For example, Sorry but I have to take leave of you now , or After the movie we'll take our leave of you . [Mid-1200s]

2. take leave of one's senses . Behave irrationally, act crazy, as in Give them the keys to the house? Have you taken leave of your senses? [Late 1800s] Also see come to one's senses .