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Alzheimer's disease

American  
[ahlts-hahy-merz, alts-, awlts-] / ˈɑlts haɪ mərz, ˈælts-, ˈɔlts- /
Or Alzheimer disease

noun

Pathology.
  1. a common form of dementia, believed to be caused by changes in the brain, usually beginning in late middle age, characterized by memory lapses, confusion, emotional instability, and progressive loss of mental ability.


Alzheimer's disease British  
/ ˈæltsˌhaɪməz /

noun

  1. Often shortened to: Alzheimer's.  a disorder of the brain resulting in a progressive decline in intellectual and physical abilities and eventual dementia

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Alzheimer's disease Scientific  
/ älshī-mərz /
  1. A progressive, degenerative disease of the brain, commonly affecting the elderly, and associated with the development of amyloid plaques in the cerebral cortex. It is characterized by confusion, disorientation, memory failure, speech disturbances, and eventual dementia. The cause is unknown. Alzheimer's disease is named for its identifier, German psychiatrist Alois Alzheimer (1864–1915).


Alzheimer's disease Cultural  
  1. A disease in which mental capacity decreases because of the breakdown of brain cells.


Discover More

Alzheimer's disease is a major cause of loss of intellectual function in middle-aged and elderly people.

Etymology

Origin of Alzheimer's disease

Named after Alois Alzheimer (1864–1915), German neurologist, who described it in 1907

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Scientists are exploring how snake venom could address cancer, strokes and Alzheimer’s disease, she said.

From Los Angeles Times • Apr. 1, 2026

The deal fits neatly into Lilly’s neuroscience business that already includes Alzheimer’s disease treatment Kisunla and the migraine shot Emgality.

From MarketWatch • Mar. 31, 2026

Jeffries' lawyers argue that he is suffering with dementia and late onset of Alzheimer's disease and is unfit to face trial alongside his partner and their alleged middleman in October.

From BBC • Mar. 28, 2026

By defining the exact microglial program responsible for clearing plaques, the findings point toward new strategies for treating Alzheimer's disease.

From Science Daily • Mar. 17, 2026

She was just beginning her long struggle with Alzheimer's disease, and each time I entered the room, I felt the need to reintroduce myself and set her at ease.

From "Me Talk Pretty One Day" by David Sedaris