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difficile

American  
[dif-i-seel, dee-fee-seel] / ˌdɪf ɪˈsil, di fiˈsil /

adjective

  1. hard to deal with, satisfy, or please.

  2. hard to do; difficult.


Etymology

Origin of difficile

1470–80; < French < Latin difficilis difficult; dif-, facile

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

But scientists noticed hints that faecal transplants for C. difficile also seemed to get rid of superbugs.

From BBC • Jun. 7, 2025

Faecal transplants – also known as a trans-poo-tion - are already approved for treating severe diarrhoea caused by Clostridium difficile bacteria.

From BBC • Jun. 7, 2025

FMT has a 90% cure rate for C. difficile infection.

From Salon • May 10, 2024

"We found reduced vancomycin susceptibility in C. difficile was associated with lower 30-day sustained clinical response and lower 14-day initial cure rates in the studied patient cohort," said Gonzales-Luna.

From Science Daily • Apr. 25, 2024

Within months, outbreaks of antibiotic-resistant Pseudomonas aeruginosa, Clostridium difficile, and E. coli are observed in patients around the world.

From "We Are the Ants" by Shaun David Hutchinson