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migraine

American  
[mahy-greyn, mee-] / ˈmaɪ greɪn, ˈmi- /

noun

  • migraines
    plural
  1. an extremely severe paroxysmal headache, usually confined to one side of the head and often associated with nausea; hemicrania.


migraine British  
/ ˈmaɪ-, ˈmiːɡreɪn /

noun

  1. a throbbing headache usually affecting only one side of the head and commonly accompanied by nausea and visual disturbances

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

migraine Scientific  
/ mīgrān′ /
  1. A severe recurring headache, usually affecting only one side of the head, that is characterized by sharp, throbbing pain and is often accompanied by nausea, vomiting, sensitivity to light, and visual disturbances. Vasodilation in the brain causes inflammation that results in pain, but the exact cause of migraine is unknown.


Other Word Forms

Derived Forms

Inflected Forms

Nouns

Etymology

Origin of migraine

First recorded in 1325–75; Middle English, from Middle French, from Late Latin hēmicrānia hemicrania; cf. megrim

Compare meaning

How does migraine compare to similar and commonly confused words? Explore the most common comparisons:

Explanation

A migraine is a severe headache. When you get a migraine, you'll probably want to stay in bed, in a dark room, until it passes. When you get a headache that's so painful that you can't work or function, you've probably got a migraine. It's usually women who get migraines, and you are either a person who gets migraines throughout your life, or you never get one at all. Migraines often come with side effects like nausea and blurred vision, and they often affect just one side of the head. The word comes from the Greek hemi-, "half" and kranion, "skull."

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Vocabulary lists containing migraine

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

What they got was a nerve-shredding night, a 90-minute rollercoaster ride, an evening to bring on a migraine.

From BBC Jun. 14, 2026

Roughly 3% of adults are also affected by vestibular migraine, a condition where migraine causes dizziness or vertigo even without a headache.

From The Wall Street Journal Apr. 15, 2026

Pfizer acquired the migraine medication through its purchase of Biohaven Pharmaceuticals in 2022.

From Barron's Feb. 3, 2026

They had 14% higher odds of reporting two or more conditions, including migraine, back problems, cancer, epilepsy or diabetes.

From Science Daily Jan. 24, 2026

He knew what migraine meant because sometimes his mother had one, only she called it my-grain and Dr. Relf had called it me-grain.

From "The Book of Dust: La Belle Sauvage" by Philip Pullman

She has now been waiting 21 months for that procedure, but has also been referred to see specialists for her bowel, bladder and migraines, as well as an ultrasound and MRI.

From BBC Apr. 22, 2026

The retired nurse, 82, said the pollution made her afraid to go out and aggravated her dizziness and migraines.

From Barron's Apr. 3, 2026

Problems with this channel have been linked to conditions such as chronic pain, migraines, dry eye and certain cancers.

From Science Daily Mar. 8, 2026

It also has access to LillyDirect, Eli Lilly & Co. digital platform for managing diabetes, obesity, and migraines.

From The Wall Street Journal Jan. 8, 2026

The dining-room table was on the verge of splintering, Clara was complaining of migraines, and Jaime was locked in his room with wax in his ears, trying to concentrate on his studies.

From "The House of the Spirits: A Novel" by Isabel Allende

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