[ ey-gam-uh-glob-yuh-luh-nee-mee-uh ]
/ ˌeɪ gæm əˌglɒb yə ləˈni mi ə /

noun Pathology.

a condition of the blood, either congenital or acquired, in which there is near or complete absence of gamma globulin and a failure of the body to form antibodies, resulting in a frequent occurrence of infectious disease.

Origin of agammaglobulinemia

First recorded in 1950–55; a-6 + gamma globulin + -emia

Related forms

a·gam·ma·glob·u·li·ne·mic, adjective Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

Medicine definitions for agammaglobulinemia


[ ā-găm′ə-glŏb′yə-lə-nēmē-ə ]


Congenital or acquired absence of, or extremely low levels of, gamma globulins in the blood.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.