noun Pathology.

a serious, acute blood disease, sometimes related to drug or radiation therapy, characterized by extreme leukopenia, fever, and ulcerations of the mucous membranes.

Nearby words

  1. agraffe,
  2. agram,
  3. agrammatism,
  4. agranular endoplasmic reticulum,
  5. agranulocyte,
  6. agranuloplastic,
  7. agrapha,
  8. agraphia,
  9. agrarian,
  10. agrarianism

Origin of agranulocytosis

First recorded in 1925–30; a-6 + granulocyte + -osis Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for agranulocytosis



a serious and sometimes fatal illness characterized by a marked reduction of leucocytes, usually caused by hypersensitivity to certain drugs

Word Origin for agranulocytosis

C20: New Latin; see a- 1, granule, -cyte, -osis

Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for agranulocytosis


[ā-grăn′yə-lō-sī-tōsĭs, ə-grăn′-]


An acute disease characterized by high fever, lesions of the mucous membranes and skin, and a sharp drop in circulating granular white blood cells.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.