[ uh-gran-yuh-loh-sahy-toh-sis ]
/ əˌgræn yə loʊ saɪˈtoʊ sɪs /

noun Pathology.

a serious, acute blood disease, sometimes related to drug or radiation therapy, characterized by extreme leukopenia, fever, and ulcerations of the mucous membranes.

Origin of agranulocytosis

First recorded in 1925–30; a-6 + granulocyte + -osis Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for agranulocytosis

/ (əˌɡrænjʊləʊsaɪˈtəʊsɪs) /


a serious and sometimes fatal illness characterized by a marked reduction of leucocytes, usually caused by hypersensitivity to certain drugs

Word Origin for agranulocytosis

C20: New Latin; see a- 1, granule, -cyte, -osis
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for agranulocytosis

[ ā-grăn′yə-lō-sī-tōsĭs, ə-grăn′- ]


An acute disease characterized by high fever, lesions of the mucous membranes and skin, and a sharp drop in circulating granular white blood cells.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.