AIDS

American  

[eydz] / eɪdz /

noun

Pathology.

1. acquired immune deficiency syndome: a disease of the immune system characterized by increased susceptibility to opportunistic infections, as pneumocystis carinii pneumonia and candidiasis, to certain cancers, as Kaposi's sarcoma, and to neurological disorders: caused by a retrovirus and transmitted chiefly through blood or blood products that enter the body's bloodstream, especially by sexual contact or contaminated hypodermic needles.

---

AIDS British  

/ eɪdz /

acronym

1. acquired immune (or immuno-)deficiency syndrome: a condition, caused by a virus, in which certain white blood cells (lymphocytes) are destroyed, resulting in loss of the body's ability to protect itself against disease. AIDS is transmitted by sexual intercourse, through infected blood and blood products, and through the placenta

---

AIDS Scientific  

/ ādz /

1. Short for acquired immune deficiency syndrome. An infectious disease of the immune system caused by an human immunodeficiency virus (HIV). AIDS is characterized by a decrease in the number of helper T cells, which causes a severe immunodeficiency that leaves the body susceptible to a variety of potentially fatal infections. The virus is transmitted in infected bodily fluids such as semen and blood, as through sexual intercourse, the use of contaminated hypodermic syringes, and placental transfer between mother and fetus. Although a cure or vaccine is not yet available, a number of antiviral drugs can decrease the viral load and subsequent infections in patients with AIDS.

---

AIDS Cultural  

1. Acronym for a cquired i mmune d eficiency s yndrome, a fatal disease caused by the human immunodeficiency virus, or HIV. Believed to have originated in Africa, AIDS has become an epidemic, infecting tens of millions of people worldwide. The virus, which is transmitted from one individual to another through the exchange of body fluids (such as blood or semen), attacks white blood cells, thereby causing the body to lose its capacity to ward off infection. As a result, many AIDS patients die of opportunistic infections that strike their debilitated bodies. AIDS first appeared in the United States in 1981, primarily among homosexuals and intravenous drug users who shared needles, but throughout the world, it is also transmitted by heterosexual contact. Today, scientists are hopeful that AIDS can be managed by new drugs, such as protease inhibitors, and need not be fatal. (See AZT.)

---

Etymology

Origin of AIDS

First recorded in 1982; a(cquired) i(mmune) d(eficiency) s(yndrome)

Example Sentences

By most accounts, the HIV drug lenacapavir is so effective in preventing infection and treating HIV-positive patients that it could revolutionize the fight against AIDS.

From Los Angeles Times • Apr. 9, 2026

Bono, 65, is well-known for his activism to eradicate poverty and fight AIDS, and has been outspoken against wars in Ukraine, Sudan and Gaza in recent years.

From Barron's • Feb. 18, 2026

It is not deadly or contagious like Ebola or AIDS.

From Slate • Dec. 19, 2025

In 1991, Mercury died at the age of 45 from bronchial pneumonia, a complication of AIDS.

From BBC • Nov. 18, 2025

There was a sign on the other side, a big piece of plywood with the letters S-I-D-A scrawled across in red paint, French for AIDS.

From "Endangered" by Eliot Schrefer

Related Words

• acquired immune deficiency syndrome
• sexually transmitted disease
• virus