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protease inhibitors

Cultural  
  1. A class of pharmaceuticals used in the treatment of AIDS. It works by blocking the action of a protein that HIV needs to reproduce itself.


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Protease inhibitors are an example of designer drugs. They sometimes allow AIDS to be managed for long periods of time.

Example Sentences

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Furthermore, viruses can mutate to evade protease inhibitors, the class of drugs Paxlovid belongs to, although researchers have not seen that happen with Paxlovid yet.

From Scientific American Feb. 8, 2023

Pfizer's drug, part of a class known as protease inhibitors, is designed to block an enzyme the coronavirus needs in order to multiply.

From Reuters Nov. 5, 2021

The protease inhibitors and other compounds look promising in cell and animal studies.

From Science Magazine Dec. 31, 2020

Signals that activate resistance traits, such as anti-digestive protease inhibitors, can be wafted on the wind or transmitted through the underground mycorrhizal networks, built by fungi, that connect plants.

From Nature Feb. 28, 2017

Soaking the seeds also breaks down phytic acid and protease inhibitors, which allows the nutrients to be more readily absorbed by the body.

From New York Times Jun. 2, 2014

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