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protease inhibitors

Cultural  
  1. A class of pharmaceuticals used in the treatment of AIDS. It works by blocking the action of a protein that HIV needs to reproduce itself.


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Protease inhibitors are an example of designer drugs. They sometimes allow AIDS to be managed for long periods of time.

Example Sentences

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Furthermore, viruses can mutate to evade protease inhibitors, the class of drugs Paxlovid belongs to, although researchers have not seen that happen with Paxlovid yet.

From Scientific American • Feb. 8, 2023

It was just after the data on these protease inhibitors had been unveiled at a major scientific conference.

From New York Times • Feb. 17, 2022

It is part of a class of drugs called protease inhibitors currently used to treat HIV, hepatitis C and other viruses.

From Reuters • Dec. 14, 2021

Baric explains that proteins in the human body bind 99% of these protease inhibitors, leaving little of them to fight viruses.

From Science Magazine • Jan. 27, 2020

Signals that activate resistance traits, such as anti-digestive protease inhibitors, can be wafted on the wind or transmitted through the underground mycorrhizal networks, built by fungi, that connect plants.

From Nature • Feb. 28, 2017