aminopeptidase

[uh-mee-noh-pep-ti-deys, -deyz, am-uh-noh-]

noun

Biochemistry.

1. any of several intestinal hydrolytic enzymes that remove an amino acid from the end of a peptide chain having a free amino group.

Word History and Origins

Origin of aminopeptidase¹

amino- + peptidase

Example Sentences

It encodes a protein called endoplasmic reticulum aminopeptidase 2, which has been shown to help immune cells recognize and fight threatening viruses.

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Changes in the code for one gene stood out: ERAP2, which encodes a protein called endoplasmic reticulum aminopeptidase 2.

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Zafgen’s beloranib works by inhibiting methionine aminopeptidase 2, a hormone.

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These peptides include a close homologue of the E/S-62 leucyl aminopeptidase of the filarioid nematode Acanthocheilonema viteae, which has been shown to inhibit B-cell, T-cell and mast cell proliferation/responses, promote an alternative activation of the host macrophages, through the inhibition of the Toll-like receptor signalling pathway, and induce a Th2 response through the inhibition of IL-12p70 production by dendritic cells.

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