Dictionary.com
Thesaurus.com

anaphylaxis

American  
[an-uh-fuh-lak-sis] / ˌæn ə fəˈlæk sɪs /

noun

Pathology.
  1. exaggerated allergic reaction to a foreign protein resulting from previous exposure to it.


anaphylaxis British  
/ ˌænəfɪˈlæksɪs /

noun

  1. extreme sensitivity to an injected antigen, esp a protein, following a previous injection

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

anaphylaxis Scientific  
/ ăn′ə-fə-lăksĭs /

Other Word Forms

  • anaphylactic adjective
  • anaphylactically adverb
  • antianaphylactic adjective
  • pseudoanaphylactic adjective

Etymology

Origin of anaphylaxis

First recorded in 1905–10; ana- + (pro)phylaxis

Compare meaning

How does anaphylaxis compare to similar and commonly confused words? Explore the most common comparisons:

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Scientists have long suspected that severe cases could escalate into life threatening anaphylaxis.

From Science Daily • Dec. 17, 2025

The immune system tries to fight them off, triggering symptoms ranging from hives and diarrhea to anaphylaxis, a life-threatening condition.

From Los Angeles Times • Oct. 20, 2025

Among the most common co-occurring illnesses were chronic fatigue syndrome and mast cell activation syndrome, or MCAS, a condition where patients experience intense episodes of diarrhea, hives, vomiting, and, in many cases, life-threatening anaphylaxis attacks.

From Slate • Sep. 15, 2025

The recommendation comes from experts who looked at food-induced anaphylaxis cases reported in Europe between 2002–2023.

From BBC • Aug. 20, 2025

May not the phenomena of anaphylaxis be studied on associational lines?

From Origin and Nature of Emotions by Crile, George W. (Washington)