androgen insensitivity syndrome

American  

[an-druh-juhn in-sen-si-tiv-i-tee sin-drohm] / ˈæn drə dʒən ɪnˌsɛn sɪˈtɪv ɪ ti ˌsɪn droʊm /

noun

1. an intersex condition in which a person has the chromosomal makeup of a male, no uterus, and certain female external sex characteristics, some of which develop at puberty, due to the body’s inability to respond to androgen hormones. AIS

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Etymology

Origin of androgen insensitivity syndrome

First recorded in 1965–70

Example Sentences

For example, females with a DSD known as androgen insensitivity syndrome have XY chromosomes; they produce testosterone; but their bodies aren’t equipped to process it.

From BBC • Aug. 8, 2024

Sean Saifa Wall is an intersex activist and researcher who was born with an intersex variation called androgen insensitivity syndrome, which occurs when a person who has XY chromosomes is resistant to hormones called androgens.

From Scientific American • Aug. 24, 2022

Many women who have androgen insensitivity syndrome never know that they have a Y chromosome.

From Washington Post • May 19, 2022

She successfully challenged her 1985 disqualification on the grounds that she also has androgen insensitivity syndrome, a condition in which her body cannot respond to testosterone, either natural or synthetic.

From Salon • Aug. 16, 2016

Under the 2011 rules, for example, women with Y chromosomes and complete androgen insensitivity syndrome were free to compete, since they can’t make use of their high levels of testosterone.

From Slate • Aug. 5, 2016