androgen insensitivity syndrome

American  

[an-druh-juhn in-sen-si-tiv-i-tee sin-drohm] / ˈæn drə dʒən ɪnˌsɛn sɪˈtɪv ɪ ti ˌsɪn droʊm /

noun

1. an intersex condition in which a person has the chromosomal makeup of a male, no uterus, and certain female external sex characteristics, some of which develop at puberty, due to the body’s inability to respond to androgen hormones. AIS

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Etymology

Origin of androgen insensitivity syndrome

First recorded in 1965–70

Example Sentences

For example, females with a DSD known as androgen insensitivity syndrome have XY chromosomes; they produce testosterone; but their bodies aren’t equipped to process it.

From BBC

What the real picture shows is that as someone with complete androgen insensitivity syndrome, which is my intersex variation, my risk of getting testicular cancer was only somewhere between one and 5% — at some point, much farther down the line in adulthood.

From Salon

Sean Saifa Wall is an intersex activist and researcher who was born with an intersex variation called androgen insensitivity syndrome, which occurs when a person who has XY chromosomes is resistant to hormones called androgens.

From Scientific American

Many women who have androgen insensitivity syndrome never know that they have a Y chromosome.

From Washington Post

“With base editors, it’s easy to create an animal model and explore pathogenic mutations all over the genome,” says Huang, who has generated mouse models of diseases such as androgen insensitivity syndrome and syndactyly, a condition in which multiple fingers or toes are fused together6.

From Nature