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Synonyms

antagonistic

American  
[an-tag-uh-nis-tik] / ænˌtæg əˈnɪs tɪk /

adjective

  1. acting in opposition; opposing, especially mutually.

  2. hostile; unfriendly.


antagonistic British  
/ ænˌtæɡəˈnɪstɪk /

adjective

  1. in active opposition

  2. mutually opposed

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of antagonistic

First recorded in 1625–35; antagonist + -ic

Explanation

If you're antagonistic, you're hard to get along with. Harmony is not your friend — you prefer hostility and struggle. If you're antagonistic to your little brother, you're always picking on him and giving him a hard time — causing him agony — a word that's buried in antagonistic. Even drugs or chemicals can be antagonistic: if you take a sleeping pill and then follow it with a few cups of espresso, the interaction is likely to be antagonistic. The sleeping pill and the caffeine struggle against each other and you're not likely to get much sleep.

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Vocabulary lists containing antagonistic

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Antagonist, a cocktail bar in Charlotte, N.C., is pretty antagonistic about phones.

From The Wall Street Journal ● Sep. 13, 2026

This concept, known as antagonistic pleiotropy, was proposed by biologist Peter Medawar in 1952 as an explanation for aspects of aging.

From Science Daily ● Aug. 26, 2026

Previously, it was his enjoyably antagonistic relationship with 1500m rival Jakob Ingebrigtsen.

From BBC ● Jun. 26, 2026

“We don’t see Airbnb as an antagonistic thing. We don’t let them take over the market, we regulate them, we charge them, and we use their tax revenue to provide services to people.”

From Los Angeles Times ● May 18, 2026

But there was no evidence that Lombardy, known for his acerbic tongue, was antagonistic toward Bobby.

From "Endgame" by Frank Brady

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