antisense

[ an-tee-sens, an-tahy‑ ]

adjective

1. of or relating to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait.

antisense

/ ăn′tē-sĕns′,ăn′tī- /

1. Relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

Word History and Origins

Origin of antisense¹

First recorded in 1985–90

Example Sentences

The other half of the mutants received the experimental drug, called antisense oligonucleotide or OL-1.

From The Daily Beast