[ an-tee-sens, an-tahy‐ ]

  1. of or relating to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait.

Origin of antisense

First recorded in 1985–90

Words Nearby antisense Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use antisense in a sentence

Scientific definitions for antisense


[ ăn′tē-sĕns, ăn′tī- ]

  1. Relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.