antisense

American

[an-tee-sens, an-tahy‑] / ˌæn tiˈsɛns, ˌæn taɪ‑ /

adjective

of or relating to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait.

antisense Scientific

/ ăn′tē-sĕns′,ăn′tī- /

Relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

Etymology

Origin of antisense

First recorded in 1985–90

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The study showed that when the researchers injected a compound called BCC10 linked to specialized genetic tools known as antisense oligonucleotides into mice, it successfully reduced the activity of harmful genes in the brain.

From Science Daily • Nov. 25, 2024

In the new study, the researchers describe how this can be achieved using the so-called "antisense" method.

From Science Daily • Feb. 29, 2024

Ultimately, antisense might be used in commercial operations to prevent maturation without genetically modifying the fish.

From Science Magazine • Feb. 9, 2023

In 1992, a geneticist at the University of Hawaii in Honolulu used antisense technology to insert a gene that blocks an enzyme in the caffeine-making pathway.

From Slate • Jan. 11, 2023

About two dozen patients have received customized antisense drugs since Dr. Yu’s announcement about Mila in 2018.

From New York Times • Dec. 19, 2022

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023