antisense

[ an-tee-sens, an-tahy‐ ]

adjective

of or relating to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait.

Origin of antisense

¹

First recorded in 1985–90

Words Nearby antisense

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

How to use antisense in a sentence

The other half of the mutants received the experimental drug, called antisense oligonucleotide or OL-1.
Trial Drug Reverses Alzheimer’s Disease in Mice | Elizabeth Lopatto | May 24, 2014 | THE DAILY BEAST

Scientific definitions for antisense

antisense

[ ăn′tē-sĕns′, ăn′tī- ]

Relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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