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apo-

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  1. a prefix occurring originally in loanwords from Greek, where it was joined to verbs, deverbal forms, and other parts of speech. Among its functions in Greek, apo- has the spatial sense “away, off, apart” (apogee; apocope; apostasy; apostrophe); it occurs with deverbals that denote a response or defense (apodosis; apology) and is found on verbs having perfective force relative to a corresponding simple verb (apoplexy; aposiopesis). In modern scientific coinages in English and other languages, apo- marks things that are detached, separate, or derivative (apocarpous; apoenzyme).
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Also especially before a vowel, ap-.

Origin of apo-

< Greek, prefixal use of apó; akin to off, Sanskrit apa, Latin ab
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for apo-

apo-

ap-

prefix
  1. away from; offapogee
  2. indicating separation ofapocarpous
  3. indicating a lack or absence ofapogamy
  4. indicating derivation from or relationship toapomorphine
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Word Origin

from Greek apo away, off
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for apo-

before vowels ap-, word-forming element meaning "from, away from, separate, free from," from Greek apo "from, away from; after; in descent from," in compounds, "from, asunder, away, off; finishing, completing; ceasing from; back again," from PIE root *apo- "off, away" (cf. Sanskrit apa "away from," Avestan apa "away from," Latin ab "away from, from," Gothic af, Old English of "away from").

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Online Etymology Dictionary, © 2010 Douglas Harper

apo- in Medicine

apo-

pref.
  1. Away from; off:aponeurosis.
  2. Separate:apocrine.
  3. Without; lacking; not:apoferritin.
  4. Related to; derived from:apomorphine.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.