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autoantibody

American  
[aw-toh-an-ti-bod-ee, -an-tee-] / ˌɔ toʊˈæn tɪˌbɒd i, -ˈæn ti- /

noun

Immunology.
autoantibodies plural
  1. an antibody that an organism produces against any of its own tissues, cells, or cell components.


autoantibody British  
/ ˌɔːtəʊˈæntɪˌbɒdɪ /

noun

  1. an antibody reacting with an antigen that is a part of the organism in which the antibody is formed

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

autoantibody Scientific  
/ ô′tō-ăntĭ-bŏd′ē /
  1. An antibody that reacts with the cells, tissues, or native proteins of the individual in which it is produced. Autoimmune diseases are caused by the presence of autoantibodies.


Other Word Forms

Noun Inflected Forms

Etymology

Origin of autoantibody

First recorded in 1905–10; auto- 1 + antibody

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Quadros’s research has found that a specific autoantibody blocks the transport of folate from mother to fetus during pregnancy and when present after birth, the infant’s brain.

From The Wall Street Journal Sep. 24, 2025

Altogether, they and Barcelona colleague Francesc Graus have uncovered 11 of the 18 known varieties: a rogue’s gallery with sharply different symptoms depending on the autoantibody responsible.

From Science Magazine May 15, 2024

Luckily, the anti-DSG3 B cells are easy to find because they have a highly distinctive marker—basically a version of the anti-DSG3 autoantibody stuck on their surfaces.

From Scientific American Sep. 20, 2021

What’s unusual about this result is that most autoantibody immune disorders appear in women, as is the case with the chronic disease lupus.

From Seattle Times Oct. 17, 2020

An antibody that inappropriately marks self-components as foreign is termed an autoantibody.

From Textbooks Apr. 25, 2013

The finger-prick blood test checks for autoantibodies - proteins that the immune system makes which can attack the body's own tissues.

From BBC Jan. 20, 2026

In diabetes, these autoantibodies attack the pancreas - the organ which has the job of making insulin to control blood sugar.

From BBC Jan. 20, 2026

The current mainstay of therapy for this life-threatening blood disorder is plasma exchange, which removes the harmful autoantibodies and provides extra ADAMTS13.

From Science Daily May 17, 2024

Bendapudi noted that the infused rADAMTS13 overwhelmed the inhibitory autoantibodies in the patient and reversed the thrombotic effects of iTTP.

From Science Daily May 17, 2024

Today, first-line immunotherapies include plasmapheresis, in which blood is circulated outside the body to purge plasma of antibodies, or an infusion of immunoglobulins—antibodies produced by plasma cells—which prompts the body to sop up autoantibodies.

From Science Magazine May 15, 2024

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