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off-label
off-labeladjectiveof, relating to, or denoting a drug prescribed for a particular indication even though the drug has not yet received approval from the Food and Drug Administration for that disease, condition, or symptom.
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off label
off labeladjective(of a prescription drug) relating to use, or being used, in ways for which it has not been approved
off-label
Americanadjective
adjective
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
See Examples For:
ME has no known cure or specific treatment, with patients often relying on off-label medication to manage a condition that can cause more than 200 symptoms, including nausea, headaches, poor cognitive function and brain fog.
From BBC ● Oct. 16, 2026
But the GLP-1s are increasingly being researched, used experimentally, and even prescribed off-label to treat a range of other conditions in which they show promise.
From The Wall Street Journal ● Sep. 18, 2026
Given that MOTS-c is already widely used off-label and no research has shown evidence of harmful side effects, Cohen said in his remarks that he believed “quality-controlled, prescriber-supervised” compounding was the safest way forward.
From Los Angeles Times ● Aug. 6, 2026
Americans became desperate for Wegovy and off-label prescriptions of Ozempic to help them lose weight.
From MarketWatch ● Aug. 5, 2026
In the United States, dentists have used it off-label since 2014, when it was approved as a medical device for reducing tooth sensitivity.
From Science Daily ● Jul. 29, 2026
The Food and Drug Administration hasn’t approved atropine for this use, but ophthalmologists sometimes prescribe a very low dose off label.
From The Wall Street Journal ● Dec. 28, 2025
Doctors began freely prescribing the Type 2 diabetes medication off label, causing a global shortage for the pricey drug, which costs about $900 a month without insurance.
From Seattle Times ● Feb. 29, 2024
TikTok has helped fuel a trend of doctors prescribing the drug off label to people for weight loss, leading to a medication shortage for diabetic patients.
From Los Angeles Times ● Jan. 25, 2023
Because sodium phenylbutyrate is already approved, doctors may prescribe it off label to ALS patients.
From Washington Post ● Sep. 6, 2022
Doctors can prescribe it off label — as they already do when prescribing it as part of a mifepristone-misoprostol combo or when using it to induce labor.
From The Verge ● May 5, 2022
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Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.