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Showing results for off-label. Search instead for b-s-lab-rel-.
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  • off-label
    off-label
    adjective
    of, relating to, or denoting a drug prescribed for a particular indication even though the drug has not yet received approval from the Food and Drug Administration for that disease, condition, or symptom.
  • off label
    off label
    adjective
    (of a prescription drug) relating to use, or being used, in ways for which it has not been approved

off-label

American  
[awf-lay-buhl, of-] / ˈɔfˈleɪ bəl, ˈɒf- /

adjective

Informal.
  1. of, relating to, or denoting a drug prescribed for a particular indication even though the drug has not yet received approval from the Food and Drug Administration for that disease, condition, or symptom.


off label British  

adjective

  1. (of a prescription drug) relating to use, or being used, in ways for which it has not been approved

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

ME has no known cure or specific treatment, with patients often relying on off-label medication to manage a condition that can cause more than 200 symptoms, including nausea, headaches, poor cognitive function and brain fog.

From BBC ● Oct. 16, 2026

But the GLP-1s are increasingly being researched, used experimentally, and even prescribed off-label to treat a range of other conditions in which they show promise.

From The Wall Street Journal ● Sep. 18, 2026

Given that MOTS-c is already widely used off-label and no research has shown evidence of harmful side effects, Cohen said in his remarks that he believed “quality-controlled, prescriber-supervised” compounding was the safest way forward.

From Los Angeles Times ● Aug. 6, 2026

Americans became desperate for Wegovy and off-label prescriptions of Ozempic to help them lose weight.

From MarketWatch ● Aug. 5, 2026

In the United States, dentists have used it off-label since 2014, when it was approved as a medical device for reducing tooth sensitivity.

From Science Daily ● Jul. 29, 2026

The Food and Drug Administration hasn’t approved atropine for this use, but ophthalmologists sometimes prescribe a very low dose off label.

From The Wall Street Journal ● Dec. 28, 2025

Doctors began freely prescribing the Type 2 diabetes medication off label, causing a global shortage for the pricey drug, which costs about $900 a month without insurance.

From Seattle Times ● Feb. 29, 2024

TikTok has helped fuel a trend of doctors prescribing the drug off label to people for weight loss, leading to a medication shortage for diabetic patients.

From Los Angeles Times ● Jan. 25, 2023

Because sodium phenylbutyrate is already approved, doctors may prescribe it off label to ALS patients.

From Washington Post ● Sep. 6, 2022

Doctors can prescribe it off label — as they already do when prescribing it as part of a mifepristone-misoprostol combo or when using it to induce labor.

From The Verge ● May 5, 2022

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