benzimidazole

[ben-zim-i-daz-ohl, ben-zuh-mid-uh-zohl]

noun

Chemistry.

1. a colorless crystalline compound, C 7 H 6 N 2 , used in organic synthesis.

Word History and Origins

Origin of benzimidazole¹

First recorded in 1925–30; benz- + imidazole

Example Sentences

"The screen was only possible because of recent progress made by our group and others in using C. elegans to study RQ-dependent metabolism, and our collaboration with RIKEN, one of Japan's biggest research agencies. We screened their world-class collection of 25,000 natural compounds, resulting in our discovery of a family of benzimidazole compounds that kills worms relying on this type of metabolism."

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Kaplan also tested for benzimidazole tolerance in worms from Worthy's housemate and from another retired greyhound, both of whom had histories of stubborn infections, and found that they were resistant.

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And the CDC warned that a new drug variety known as benzimidazole opioids has “begun appearing in cities across the country … adding a new threat to public health.”

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By sequencing the tapeworm's genome, they pinpointed genes that provide resistance to a drug called benzimidazole, and other genes that suggest a possible sensitivity to another tapeworm drug, praziquantel.

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