bradykinin

American  

[brad-i-kin-in, -kahy-nin] / ˌbræd ɪˈkɪn ɪn, -ˈkaɪ nɪn /

noun

Biochemistry.

1. a peptide hormone that dilates peripheral blood vessels and increases capillary permeability.

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bradykinin British  

/ ˌbreɪdɪ-, ˌbrædɪˈkaɪnɪn /

noun

1. a peptide in blood plasma that dilates blood vessels and causes contraction of smooth muscles. Formula: C 50 H 73 N 15 O 11

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Etymology

Origin of bradykinin

First recorded in 1945–50; brady- + -kinin

Example Sentences

On the other hand, these drugs increase the concentration of the vasoactive signaling substance bradykinin.

From Science Daily • Jan. 31, 2024

That disease results from mutations that disable a protein called C1-esterase inhibitor that’s part of a signaling pathway controlling levels of bradykinin, a peptide hormone that causes blood vessels to leak fluid.

From Science Magazine • Sep. 16, 2022

If you’re out in the sun too long, the resulting sunburn will set in motion a cascade of inflammatory processes in your skin, including the production of compounds called prostanoids and bradykinin.

From Scientific American • Feb. 4, 2015

Additionally, bradykinin, a vasodilator, is released, reversing the effects of the serotonin and prostaglandins from the platelets.

From Textbooks • Jun. 19, 2013

By using RMP-7, a synthetic version of bradykinin, Black's team has been able to focus chemotherapy drugs right on the tumors, increasing the effective dose as much as 10-fold.

From Time Magazine Archive