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BRCA

¹ American

noun

either of two genes BRCA1 or BRCA2 that, if inherited in a mutated form, may predispose some carriers to develop breast or ovarian cancer.

B.R.C.A. ² American

abbreviation

Brotherhood of Railway Carmen of America.

BRCA Scientific

/ bē′är′sē′ā′ /

One of two genes (designated BRCA1 and BRCA2) that help repair damage to DNA, but when inherited in a defective state increase the risk of breast and ovarian cancer.

Etymology

Origin of BRCA

1900–95; initialism from br(east) and ca(ncer)

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

She said she tested negative for all of them, including BRCA, the most well-known breast cancer gene.

From New York Times

He said scientific research has not been hindered by the biotechnology company's patents, citing 18,000 scientists who have published 10,000 papers on BRCA.

From Reuters

Dr. Hulick said the risk of developing breast cancer was 40 percent to 60 percent greater among women with the PALB2 mutation, similar to the risk from BRCA.

From New York Times

"I think we could have moved a lot faster if the country's scientific brainpower could have analyzed patients' BRCA" rather than rely on Myriad, said Chung.

From Reuters

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023