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cachectin

[ kuh-kek-tin ]
/ kəˈkɛk tɪn /
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noun

Biochemistry, Immunology. a protein that is released by activated macrophages as an immune system defense and, when the defense is overwhelmed, is a cause of cachexia or toxic shock: in humans, identical with tumor necrosis factor.

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Origin of cachectin

<Greek kachekt(ikós) unwell (see cachexia, -tic) + -in2
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2021

Medical definitions for cachectin

cachectin
[ kə-kĕktĭn ]

n.

A polypeptide hormone produced by macrophages that releases fat and reduces the concentration of enzymes needed to produce and store fat.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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