centrosome

[sen-truh-sohm]

noun

Cell Biology.

1. a small region near the nucleus in the cell cytoplasm, containing the centrioles.

centrosome

/ ˌsɛntrəˈsɒmɪk, ˈsɛntrəˌsəʊm /

noun

1. Also called: centrosphere. a small body in a cell where microtubules are produced. In animal cells it surrounds the centriole

centrosome

1. A specialized region of the cytoplasm that is located next to the nucleus of a cell and contains the centrioles. The cells of most eukaryotes except plants have centrosomes.

Other Word Forms

• centrosomic adjective

Word History and Origins

Origin of centrosome¹

First recorded in 1895–1900; centro- + -some ³

Example Sentences

But in neurons -- which don't divide -- the stimulated centrosomes participated in cycles of DNA repair that appeared to organize individual neurons into memory assemblies.

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Asymmetric centrosome inheritance maintains neural progenitors in the neocortex.

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When Hh signaling is disrupted, centrosome polarization to the immunological synapse is reduced, and cytotoxic T cell–mediated killing is impaired.

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Examples of excessive instability resulting in cell lethality can be observed in the context of mitotic checkpoint dysfunction or multipolar anaphases in cells with extra centrosomes.

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At the end, we were able to see an entire centrosome in a miotic HeLa cell.

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