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cerebrospinal

American  
[suh-ree-broh-spahyn-l, ser-uh-] / səˌri broʊˈspaɪn l, ˌsɛr ə- /

adjective

Anatomy, Physiology.
  1. pertaining to or affecting the brain and the spinal cord.

  2. of or relating to the central nervous system.


cerebrospinal British  
/ ˌsɛrɪbrəʊˈspaɪnəl /

adjective

  1. of or relating to the brain and spinal cord

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of cerebrospinal

First recorded in 1820–30; cerebro- + spinal

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

To administer genetic medicines against the tau protein tangles that are Alzheimer’s’ other main pathology, doctors must inject them directly into the cerebrospinal fluid.

From Barron's Jun. 3, 2026

Using this technology, the team monitored the movement of cerebrospinal and interstitial fluids along the MMA in five healthy individuals over six hours.

From Science Daily Apr. 9, 2026

During those misses, the scientists observed a surge of cerebrospinal fluid through and out of the brain.

From The Wall Street Journal Feb. 13, 2026

Previously, the only way to confirm Alzheimer's was by specialist PET brain scans and lumbar punctures to extract cerebrospinal fluid.

From BBC Sep. 9, 2025

It’s a fine large word, and is in my line; it has quite a learned and cerebrospinal incandescent sound. 

From A Horse's Tale by Twain, Mark

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