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chromatin

American  
[kroh-muh-tin] / ˈkroʊ mə tɪn /

noun

Cell Biology.
  1. the readily stainable substance of a cell nucleus, consisting of DNA, RNA, and various proteins, that forms chromosomes during cell division.


chromatin British  
/ ˈkrəʊmətɪn /

noun

  1. cytology the part of the nucleus that consists of DNA and proteins, forms the chromosomes, and stains with basic dyes See also euchromatin heterochromatin

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

chromatin Scientific  
/ krōmə-tĭn /
  1. The substance distributed in the nucleus of a cell that condenses to form chromosomes during cell division. It consists mainly of DNA and proteins called histones.


Other Word Forms

Etymology

Origin of chromatin

First recorded in 1880–85; chromat- + -in 2

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

"We're capturing not just gene expression, but also RNA dynamics and chromatin state," says Cao.

From Science Daily May 21, 2026

"For years, we've used these equations to study how chromatin, which is the folded state of DNA inside the nucleus, organizes itself inside living cells," says Shenoy.

From Science Daily May 6, 2026

By estimating the rates of epigenetic reactions, which control gene activity, the new AI method could help scientists move beyond simply observing chromatin to predicting how it changes over time.

From Science Daily May 6, 2026

BET inhibitors were designed to block a shared feature that all BET proteins use to attach to chromatin, the tightly packed structure of DNA and proteins where genes are stored and controlled.

From Science Daily Apr. 9, 2026

No one knew or understood the chemical structure of chromatin, but of the two “intimately mixed” components, proteins were vastly more familiar to biologists, vastly more versatile, and vastly more likely to be gene carriers.

From "The Gene" by Siddhartha Mukherjee

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